Dave:
As I understand it (with information from John Armstrong’s Track Planning for Realistic Operation, 2nd edition), the real railroads rate curves in degrees changed per 100 feet of run. If you do the math out for a 5 degree curve (that’s 5 degrees in each 100 feet of run), you get a radius of 1,147’ 4.6".
When you convert that to O, you get a radius of about 286.8 inches, or about 24’. So, you’d need about 48’ to make a single half-circle out of a 5 degree turn.
A 1 degree turn, which is probably closer to the type of turn for 80 MPH, has a radius in O of 1432.5 inches, or 119’ 4.5".
I think you’d need a space the size of the Boeing airplane factory to build an O gauge layout using true scale curves.
Tony