I-35 in Austin, TX has an upper and lower I-35. Minneapolis and St. Paul each have their own I-35 designated as E & W. So you can go North or South on East or West, but you cannot go East or West, got that? Duluth, MN has a traffic light on I-35 at the (infamous) can of worms. Only one traffic death has been recorded there. A lot of rerouting of tracks were required to “fit” in the interstate. I-35 was to have continued through Duluth to Two Harbors, MN which was set up with a grade level crossing of the DM&IR. This was down graded to an expressway and the grade crossing never was built.
I think that at the rate the US 17 to I86 upgrade is going it will take another 30 to 50 years. But there are some nice stretches to it.